Matthew Cascio

Matthew Cascio, DO

Assistant Professor

Department: MD-PEDS-HEMATOLOGY
Business Phone: (352) 273-9120
Business Email: mcascio@ufl.edu

About Matthew Cascio

Matthew Cascio, DO, is an assistant professor in the division of hematology and oncology in the department of pediatrics in the University of Florida College of Medicine.

After he achieved his bachelor’s degree in sociology from the Ohio State University in Columbus, Ohio, Dr. Cascio graduated with his doctor of osteopathy degree from Nova Southeastern University College of Osteopathic Medicine in Fort Lauderdale, Florida. He then pursued his residency in pediatrics at Penn State University College of Medicine in Hershey, Pennsylvania. The following year, Dr. Cascio completed his fellowship in the division of pediatric hematology and oncology at UF Health Shands Children’s Hospital.

Dr. Cascio is board-certified in pediatrics by the American Board of Pediatrics. Throughout his academic career, he was involved with various associations, such as the American Academy of Pediatrics and the Children’s Oncology Group. He has also received numerous honors, like the Sarcoma Foundation of America Award and Douglas J. Barrett Fellow Research Award. Dr. Cascio has extensive experience in research, with his interests including brain tumors, immunotherapy and programmatic development.

Dr. Cascio currently serves as the Interim Clinical Director of Pediatric Neuro-Oncology, and he is passionate about childhood advocacy, mentorship and clinical research.

Teaching Profile

Courses Taught
2018
MDC7400 Pediatric Clerkship
2018
MDC7401 Senior Pediatric Clk

Board Certifications

  • Pediatrics
    American Board of Pediatrics

Clinical Profile

Specialties
  • Pediatrics
Subspecialties
  • Hematology and Oncology
Areas of Interest
  • Brain tumor – children
  • Cancer – resources
  • Neurofibromatosis 2
  • Neurofibromatosis-1
  • Tuberous sclerosis

Research Profile

The research efforts of Dr. Cascio are supported by STOP Children’s Cancer.

Areas of Interest
  • Brain Tumors
  • Immunotherapy
  • Programmatic Development

Publications

2021
Canine osteosarcoma checkpoint expression correlates with metastasis and T-cell infiltrate.
Veterinary immunology and immunopathology. 232 [DOI] 10.1016/j.vetimm.2020.110169. [PMID] 33387703.
2021
Novel application of single-cell next-generation sequencing for determination of intratumoral heterogeneity of canine osteosarcoma cell lines.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 33(2):261-278 [DOI] 10.1177/1040638720985242. [PMID] 33446089.
2017
A Case Presentation: Rare Occurrence of an Adolescent Male Presenting With an ATRT and Simultaneous Low-grade Glioneuronal Tumor.
Journal of pediatric hematology/oncology. 39(8):e456-e459 [DOI] 10.1097/MPH.0000000000000871. [PMID] 28731919.

Grants

Dec 2017 – Aug 2021
An Immunological Strategy to Osteosarcoma: Reconditioning the Immune System with Adoptive CAR-T Cells and Reversal of Regulatory Pathways.
Role: Principal Investigator
Funding: HYUNDAI HOPE ON WHEELS
Jun 2017 – Apr 2019
CART Cells for Sarcoma
Role: Principal Investigator
Funding: Sarcoma Foundation of America

Education

Fellowship, Pediatric Hematology/Oncology
2014-2017 · University of Florida College of Medicine
Residency, Pediatrics
2011-2014 · Penn State University College of Medicine
Doctor of Osteopathy Degree
2007-2011 · Nova Southeastern University College of Osteopathic Medicine
Bachelor's Degree, Sociology
2002-2006 · The Ohio State University

Contact Details

Phones:
Business:
(352) 273-9120
Emails:
Business:
mcascio@ufl.edu
Addresses:
Business Mailing:
PO Box 100296
GAINESVILLE FL 32610
Business Street:
1600 SW ARCHER RD
GAINESVILLE FL 32610