Clinical Trials

Our clinical research program offers clinical trials for childhood leukemia, lymphoma, sarcoma, brain tumors and other rare tumors as well as sickle cell disease, hemophilia and other bleeding disorders.  Our oncology portfolio of studies includes phase 1 – 3 studies from the Children’s Oncology Group (COG), Beat Children’s Cancer, National Pediatric Cancer Foundation, the Pediatric Neuro-oncology Consortium as well as grant funded investigator-initiated studies and collaborative studies with other nationally renowned academic sites. Our current list of active trials can be found blow.

The Pediatric Research Hub provide trials for sickle cell disease, hemophilia and other bleeding disorders and oversee the American Thrombosis and Hemostatsis Network (ATHN) registry. The Pediatric Neurosurgery Research staff oversee the studies we offer for pediatric and young adult brain tumors.  


Active Trials

ATHN 10

Investigator
Tung T Wynn
Location
Gainesville

NYMC-571

This is a follow-up trial to NYMC 526 (NCT01461837) to assess the safety, efficacy and toxicity of administering Defibrotide prophylaxis for high-risk sickle…

Investigator
Jordan Milner
Protocol ID
NCT02675959
Ages
6 Months – 34 Years
Sexes
All
Location
Gainesville

OBS17523

This is a prospective, observational, multi-center longitudinal cohort study to describe the real-world effectiveness, safety and treatment usage of…

Investigator
Tung T Wynn
Protocol ID
NCT05911763
Ages
N/A – N/A
Sexes
All
Location
Gainesville

OMS721-HCT-002

The purpose of this study is to evaluate the safety and efficacy of narsoplimab in pediatric patients with thrombotic microangiopathies (TMA) following…

Investigator
John Ligon
Protocol ID
NCT05855083
Ages
28 Days – 17 Years
Sexes
All
Location
Gainesville

R0000-HEMB-2187

This study is focused on males who have Hemophilia B and who need regular preventive treatment with factor IX protein (FIX) replacement therapy to prevent and…

Investigator
Tung T Wynn
Protocol ID
NCT05568459
Ages
16 Years – N/A
Sexes
Male
Location
Gainesville