Our clinical research program offers clinical trials for childhood leukemia, lymphoma, sarcoma, brain tumors and other rare tumors as well as sickle cell disease, hemophilia and other bleeding disorders. Our oncology portfolio of studies includes phase 1 – 3 studies from the Children’s Oncology Group (COG), Beat Children’s Cancer, National Pediatric Cancer Foundation, the Pediatric Neuro-oncology Consortium as well as grant funded investigator-initiated studies and collaborative studies with other nationally renowned academic sites. Our current list of active trials can be found blow.
The Pediatric Research Hub provide trials for sickle cell disease, hemophilia and other bleeding disorders and oversee the American Thrombosis and Hemostatsis Network (ATHN) registry. The Pediatric Neurosurgery Research staff oversee the studies we offer for pediatric and young adult brain tumors.
Active Trials
(FPBCC) Retrospective CIBMTR Data Analysis
- Investigator
- Jordan Milner
- Location
- Gainesville
ATHN 10
- Investigator
- Tung T Wynn
- Location
- Gainesville
ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders
In parallel with the growth of ATHN’s clinical studies, the number of new therapies for all blood disorders is increasing significantly. Some of the recently…
- Investigator
- Tung T Wynn
- Protocol ID
- NCT04398628
- Ages
- N/A – N/A
- Sexes
- All
- Location
- Gainesville
Hemophilia Registry
- Investigator
- Tung T Wynn
- Location
- Gainesville
NYMC-571
This is a follow-up trial to NYMC 526 (NCT01461837) to assess the safety, efficacy and toxicity of administering Defibrotide prophylaxis for high-risk sickle…
- Investigator
- Jordan Milner
- Protocol ID
- NCT02675959
- Ages
- 6 Months – 34 Years
- Sexes
- All
- Location
- Gainesville
NYMC-600
This research study is being done to determine the safety and tolerability of increasing doses of defibrotide within a single patient with sinusoidal…
- Investigator
- Jordan Milner
- Protocol ID
- NCT05987124
- Ages
- 1 Month – 75 Years
- Sexes
- All
- Location
- Gainesville
OBS17523
This is a prospective, observational, multi-center longitudinal cohort study to describe the real-world effectiveness, safety and treatment usage of…
- Investigator
- Tung T Wynn
- Protocol ID
- NCT05911763
- Ages
- N/A – N/A
- Sexes
- All
- Location
- Gainesville
OMS721-HCT-002
The purpose of this study is to evaluate the safety and efficacy of narsoplimab in pediatric patients with thrombotic microangiopathies (TMA) following…
- Investigator
- John Ligon
- Protocol ID
- NCT05855083
- Ages
- 28 Days – 17 Years
- Sexes
- All
- Location
- Gainesville
R0000-HEMB-2187: HONEY-B
This study is focused on males who have Hemophilia B and who need regular preventive treatment with factor IX protein (FIX) replacement therapy to prevent and…
- Investigator
- Tung T Wynn
- Protocol ID
- NCT05568459
- Ages
- 16 Years – N/A
- Sexes
- Male
- Location
- Gainesville
R131L1265-HEMB-2318; BEYOND-9
Participants in this study have a genetic mutation, specifically in the coagulation (blood clotting) Factor 9 gene that causes severe or moderately severe…
- Investigator
- Tung T Wynn
- Protocol ID
- NCT06379789
- Ages
- 2 Years – N/A
- Sexes
- Male
- Location
- Gainesville